Platelets are most important to provide cellular hemostasis but also take part in inflammation and immune processes. Increased platelet

 

Abstract

Platelets are most important to provide cellular hemostasis but also take part in inflammation and immune processes. Increased platelet size has been regarded as a feature describing a young and more reactive subpopulation until studies were published which questioned this concept. Changes of platelet size given by the mean platelet volume (MPV) were described for immune thrombocytopenia, cardiovascular disease, atherosclerosis, venous thromboembolism, chronic lung disease, sepsis, cancer associated thrombosis, autoimmune disorders and others. This review summarizes the literature on what is known about platelets with different size and describes controversies of studies with large and small platelets putting a focus on their thrombogenicity and age in functional studies and on the association of MPV with the mentioned diseases.

PMID: 32108994 [PubMed - as supplied by publisher]

1 March 2020

12:25

Cancer & Heart (Cardio-Oncology, Cardiotoxicity, TEV)

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INCREASED RISK OF SEVERE MATERNAL MORBIDITY AMONG INFERTILE WOMEN: ANALYSIS OF US CLAIMS DATA.

Am J Obstet Gynecol. 2020 Feb 26;:

Authors: Murugappan G, Li S, Lathi RB, Baker VL, Luke B, Eisenberg ML