vascular or lymphatic insufficiency, surgical procedures, and
decubitus ulcers. The past medical history can be r elevant, as
that depresses the immune system ( eg, steroids,
diabetes, immunosuppressive drugs, elderly) predisposes the
patient to soft tissue infections and may mask the severity of
illness. Also, the status of tetanus immunization and previous
antibiotic allergies should be ascertained.
Vitals signs provide rapid clues to the severity of infection.
Tachycardia and hypotension may indicate sepsis. Fever is
not reliable, as it occurs in <10% of patients with simple
..&. Figure 36-1 . A. Cellu litis of the left leg.
B. Lymphangitis of the arm in a patient with a hand
infection. C. Necrotizing fasciitis of the lower extremity.
This patient req uired amputation of the leg to treat his
infection. Cou rtesy of Kevin jones, MD. D. Fournier's
gangrene extending up the back of a patient.
The skin examination is crucial, and it is important to
completely undress the patient to examine the involved
body part. Assess the involved area for erythema, warmth,
edema, and tenderness (Figure 36- lA). Lack of tenderness
helps differentiate infections from other causes of skin
erythema and warmth, such as venous stasis. Evidence of
lymphatic spread in the form of red lines tracking proximally
from the wound, called lymphangitis, further suggests an
infectious etiology (Figure 36-lB). Focal areas of fluctuance
and induration may indicate abscess formation.
Marking the extent of erythema on the patient with a
pen will allow for comparison on repeat examinations.
Rapid extension is concerning for a necrotizing infection
(Figures 36-lC and D). Crepitus suggests gas formation in
few findings on physical exam. The absence of crepitus
does not rule out a deep space infection.
Distal pulses should be examined to assess for arterial
The diagnosis of simple cellulitis, erysipelas, or an abscess
is clinical. Basic laboratory studies, such as a complete
blood count or basic metabolic panel, are of little benefit.
However, they should be considered if there is a s uspicion
of necrotizing infection, immune compromise, a history
suggestive of hyperglycemia/metabolic abnormalities, or
significantly elevated. Gram stain and wound culture
should be obtained in patients with suspected MRSA
abscess and necrotizing infections, as it will guide future
antibiotic therapy. Routine blood cultures add little to the
diagnosis and treatment of soft tissue infections .
Ultrasound is becoming more frequently utilized in the ED
for the diagnosis of cutaneous abscesses. It is fast, readily
available at the bedside, and can easily localize an abscess
for incision and drainage (Figure 36-2A). Ultrasound is
also more sensitive than plain radiographs for soft tissue
Figure 36-2. A. U ltrasound of a cutaneous abscess.
The abscess cavity is hypoechoic with mixed interna l
echogenicity. The surrounding skin is hyperechoic
fasciitis of the abdominal wall (a rrow).
air. Plain radiographs are helpful to evaluate for traumatic
injury, osteomyelitis, and the presence of gas formation
(Figure 36-2B). However, radiographs are insensitive for
small amounts of air. Computed tomography scan remains
the most sensitive for soft tissue air, deep space abscesses,
and foreign bodies (Figure 36-2C).
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