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(1) Necessitating more frequent suctioning
c. Procedures requiring repositioning infant
E. Technique (See also Endotracheal
Techniques of Intubation Specific to
Unique Patient Needs) Orotracheal
1. Position infant with the head in midline and the neck
slightly extended, pulling chin into a “sniff” position
(Fig. 36.4). The head of the infant should be at operator’s eye level.
It may be helpful to place a roll under the baby’s
shoulders to maintain slight extension of the neck.
3. Clear oropharynx with gentle suctioning.
with the blade directed toward patient.
a. Put thumb over flat end of laryngoscope handle.
b. Stabilize the infant’s head with right hand.
The laryngoscope is designed to be held in the
of the blade may block the view of the glottis, as
well as make insertion of the endotracheal tube
7. Open infant’s mouth and depress tongue toward the left
with the back of right forefinger (Fig. 36.5).
a. Continue to steady head with third fourth and fifth
b. Do not use the laryngoscope blade to open mouth.
8. Under direct visualization, insert the laryngoscope
blade, sliding over the tongue until the tip of the blade
laryngoscope blade, will improve visibility.
Fig. 36.4. Appropriate sniff position for intubation. Note that
the neck is not hyperextended; the roll provides stabilizing
Fig. 36.1. A: Vallecula cyst, causing stridor and proximal airway
obstruction. B: Endotracheal tube passes beneath cyst. C: Same
patient after laser surgical treatment.
Tube Size (ID mm) Weight (g) Gestational Age (wk)
238 Section VI ■ Respiratory Care
b. Secure tube carefully in position to avoid dislodgement, kinking, or movement.
(1) Vary contact point from side to side to prevent
damage to developing palate and palatal ridges
(2) Note relationship of head position to intratracheal depth of tube on radiograph (9).
resistance is lost by bypassing the upper airway.
10. Recognize that in neonates, endotracheal tubes are
often pushed in too far because of the short distance
from the glottis to the carina. Use a standardized graph
11. Recognize the association of a short trachea (fewer than
15 tracheal cartilage rings) with certain syndromes:
DiGeorge syndrome, skeletal dysplasias, brevicollis,
congenital rubella syndrome, interrupted aortic arch,
and other congenital syndromes involving the tracheal
Fig. 36.2. Anatomic view of neonatal upper airway. The glottis
sits very close to the base of the tongue, so visualization is easiest
without hyperextending the neck.
Table 36.2 Trouble-Shooting Problems with Endotracheal Intubation
Problem Suggested Approach for Solution
Infant’s tongue gets in way. Push tongue aside with finger before inserting blade.
Secretions prevent visualization. Suction prior to intubation attempt.
Vocal cords are closed. Decrease angle of neck extension.
Apply a short puff of air through the tube onto the vocal
Unsure of appropriate tube length. Await spontaneous breath.
Apply gentle suprasternal pressure.
Difficult to ventilate after intubation. Insert tube just past vocal cord.
Obtain chest radiograph with head in neutral position to
confirm tube position relative to carina.
Swelling of neck and anterior chest. Verify that tube is in trachea.
Verify that tube is not in bronchus.
Consider tube and/or airway obstruction.
Consider pulmonary air leak into mediastinum/pericardium (Fig. 38.8A, B)
Blood return from endotracheal tube. Evaluate for tracheal perforation.
Tube slips into main bronchus. Avoid neck hyperextension.
Maintain correct lip-to-tip distance.
Unplanned extubation. Regularly verify correct tube distance.
Secure tape and replace as necessary.
Support neck when moving infant.
Avoid neck hyperextension or traction on tube.
Chapter 36 ■ Endotracheal Intubation 239
12. Identify and prevent the factors that are most likely to
a. Miller blade size 1 for full-term infant
b. Miller blade size 0 for preterm infant (size 00 for
extremely low birth weight infant)
Straight rather than curved blades are preferred
c. Modified blade to allow continuous flow of oxygen
at 1 to 2 L/min for better maintenance of oxygenation during procedure. The use of a Viewmax
(Rusch, Duluth, Georgia) laryngoscope improves
viewing of the larynx but requires a longer time for
9. Humidified oxygen/air source, blender, and analyzer
10. Resuscitation bag and mask
13. Pulse oximetry oxygen saturation monitor
15. Adhesive tape: Two 8- to 10-cm lengths of 0.5-inch-wide
tape, with half the length split and one 10- to 15-cm
Chapter 36 ■ Endotracheal Intubation 237
1. Select orotracheal route for all emergency intubations
2. Prepare all equipment before starting procedure. Keep
equipment ready at bedside of patients likely to require
3. Use appropriate-size tubes (Table 36.1). To minimize
upper airway trauma, the tube should not fit tightly
4. To minimize hypoxia, each intubation attempt should
be limited to 20 seconds. Interrupt an unsuccessful
suspected congenital diaphragmatic hernia.
5. Recognize anatomic features of neonatal upper airway
6. Ensure visualization of larynx. This is the most important step (Fig. 36.3).
a. Have an assistant maintain proper position of
b. Avoid hyperextending or rotating neck.
7. Do not use pressure or force that may predispose to
a. Avoid using maxilla as fulcrum for laryngoscope
b. Avoid excessive external tracheal pressure.
c. Avoid pushing tube against any obstruction.
8. Make certain all attachments are secure.
a. Avoid obscuring the point of connection of tube and
Chapter 35 ■ Bubble Nasal Continuous Positive Airway Pressure 235
1. Gregory GA, Kitterman JA, Phibbs RH, et al. Treatment of the
idiopathic respiratory distress syndrome with continuous positive
airway pressure. N Engl J Med.1971;384:133.
2. Gregory GA. Devices for applying continuous positive pressure.
In: Thibeault DW, Gregory GA, eds. Neonatal Pulmonary Care.
Menlo Park, CA: Addison-Wesley; 1979.
4. Wung JT. Continuous positive airway pressure. In: Wung JT. (ed)
Respiratory care of the newborn: A practical approach. New York:
Columbia University Medical Center; 2009.
5. Aly H. Nasal prongs continuous positive airway pressure: a simple
yet powerful tool. Pediatrics. 2001;108:759.
6. Aly H, Massaro AN, Patel K, et al. Is it safer to intubate premature
infants in the delivery room? Pediatrics. 2005;115:1660.
7. Nowadzky T, Pantoja A, Britton JR. Bubble continuous positive
pressure, a potentially better practice, reducing the use of
mechanical ventilation among very low birth weight infants with
respiratory distress syndrome. Pediatrics. 2009;123:1534.
infants: work of breathing and gas exchange. J Perinatol. 2011;
9. Jobe AH, Kramer BW, Moss TJ, et al. Decreased indicators of
lung injury with continuous positive expiratory pressure in preterm lambs. Pediatr Res. 2002;52:387.
10. Zhang S, Garbutt V, McBride JT. Strain-induced growth of the
immature lung. J Appl Physiol. 1996;81:1471.
11. Lemyre B, Davis PG, dePaoli AG. Nasal intermittent positive
Database Syst Rev.2002;1:CD002272.
12. Bonner K.M, Mainous R.O. The nursing care of the infant
receiving bubble CPAP therapy. Adv Neonatal Care. 2008;8(2):78.
13. Abdel-Hady H, Shouman B, Aly H. Early weaning from CPAP to
14. Aly H, Massaro AN, Hammad TA, et al. Early nasal continuous
positive airway pressure and necrotizing enterocolitis in preterm
Fig. 35.3. An infant with CPAP properly attached to the head.
(1) Head cap (cap fit well on head covering down to eye brows,
almost entire ears and back of head); (2) breathing circuit tubes
attached to side of hat while avoiding both eyes; (3) three-way
elbow on expiratory limb allows the attachment of pressure
manometer or could be capped to preserve pressure within circuit;
(4) orogastric tube attached to lower lip and chin with Tegaderm;
(5) neck roll allowing slight neck extension (sniff position); (6)
nasal prongs applied to baby—prongs inserted into nares allowing
a space between the transverse arm of the nasal prongs and nose to
avoid damage to nasal columella; (7) supporting chin strip.
Infant should be assessed during the trial for any
tachypnea, retractions, oxygen desaturation, or
apnea. If any of these signs are observed, the trial is
considered failed. Infant should be restarted immediately on CPAP, for at least 24 hours, before
c. Do not wean the infant off b-CPAP if there is any
likelihood of respiratory compromise during the
weaning process. It is wise to anticipate and prevent
lung collapse, rather than risk having to manage collapsed lungs.
d. Do not wean infants off b-CPAP if they require supplemental oxygen. (13)
a. Nasal obstruction: From secretions or improper
positioning of b-CPAP prongs. To avoid obstruction,
nares should be suctioned frequently and prongs
checked for proper placement. Never use a nasal–
pharyngeal tube to supply b-CPAP, because of significant risk of nasal airway obstruction.
b. Nasal septal erosion or necrosis: Due to pressure
on the nasal septum. This can be avoided by maintaining a small space (use DuoDERM 2 to
3 mm) between the bridge of the prongs and the
septum. Choosing the proper-sized snug-fitting
nasal prongs, using a Velcro mustache to secure
the prongs in place, and avoiding pinching of the
nasal septum, will minimize the risk of septal
injury. Significant nasal septal erosion may require
consultation with the ENT or Plastic Surgery
indwelling orogastric tube because secretions may
block the tube and lead to distention.
place so that it cannot be displaced to produce
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ABSTRACT Doxorubicin (Dox) is a highly potent chemotherapy drug. Despite its efficacy, Dox's clinical application is limited due to it...









































































































