c

linic

a

l

p

r

e

s

e

nt

a

t

io

n

,

5

2

0

d

e

finit

io

n

a

n

d

e

p

id

e

mio

lo

gy

,

5

1

9

e

t

io

lo

gy

,

5

1

9

p

a

th

o

g

e

n

e

s

is

,

5

1

9

–

5

2

0

tr

e

a

tme

nt

,

5

2

0–

5

2

4

ir

r

it

a

b

le

b

o

w

e

l

s

yn

dr

o

me

a

s

s

o

c

ia

t

e

d

p

a

in

a

n

d

b

lo

a

t

in

g

,

5

3

5

–

5

3

6

dia

gn

o

s

is

,

5

3

2

–

5

3

4

w

ith

dia

r

r

h

e

a

,

5

3

6

e

t

io

lo

gy

,

5

3

2

ma

n

a

g

e

me

nt

,

5

3

4

p

a

th

op

hy

s

io

lo

gy

,

5

3

2

p

h

a

r

ma

c

o

th

e

r

a

p

y

fo

r

c

o

n

s

t

ip

a

t

io

n

-

p

r

e

do

min

a

nt

,

5

3

4–

5

3

5

ulc

e

r

a

t

iv

e

c

o

lit

is

p

a

th

op

hy

s

io

lo

gy

a

n

d

c

linic

a

l

p

r

e

s

e

nt

a

t

io

n

,

5

2

4–

5

2

5

r

e

mis

s

io

n

in

du

c

t

io

n

,

5

2

5

–

5

2

6

r

e

mis

s

io

n

ma

int

e

n

a

n

c

e

,

5

2

7

–

5

2

8

v

a

c

c

in

a

t

io

n

s

in

I

B

D

p

a

t

ie

nt

,

5

2

8

L

o

wm

o

l

e

c

u

l

a

r

we

i

g

h

t

h

e

p

a

ri

n

s

(

L

M

WH

)

,

6

5

6

L

o

wri

s

k

p

u

l

m

o

n

a

ry

e

m

b

o

l

i

s

m

(

P

E

)

,

1

8

9

L

Q

T

S

(

s

e

e

L

o

n

g

Q

T

s

y

n

d

r

o

m

e

(

L

Q

T

S

)

)

L

u

n

g

A

l

l

o

c

a

t

i

o

n

S

c

o

r

e

,

4

6

4

p. 2

3

5

0

p. 2

3

5

1

L

u

n

g

c

a

n

c

e

r

a

n

d

c

ig

a

r

e

tt

e

s

mo

kin

g

,

1

9

0

5

,

1

9

1

8

c

umula

t

iv

e

r

is

k

o

f

d

e

a

th

fr

o

m

,

2

0

6

1

t

n

e

o

a

dj

uv

a

nt

th

e

r

a

p

y

,

1

9

5

8

n

o

n

-

s

ma

llc

e

ll

(

N

S

C

L

C

)

,

1

9

5

8

t

,

2

0

6

0–

2

0

6

6

a

n

d

p

o

s

tme

n

op

a

u

s

a

l

h

o

r

mo

n

e

th

e

r

a

p

y

,

1

0

3

2

t

s

ign

s

a

n

d

s

ymp

t

o

m

s

fo

r

,

2

0

6

0

t

s

it

e

s

o

f

me

t

a

s

t

a

s

e

s

,

1

9

5

0

t

s

ma

ll

c

e

ll

(

S

C

L

C

)

,

2

0

6

6–

2

0

6

9

L

u

n

g

,

d

r

u

g

h

yp

e

r

s

e

n

s

i

t

i

v

i

t

y

r

e

a

c

t

i

o

n

s

i

n

,

6

9

2

L

u

n

g

t

r

a

n

s

p

l

a

n

t

a

t

i

o

n

,

4

6

4

L

u

n

g

v

o

l

u

m

e

r

e

d

u

c

t

i

o

n

s

u

r

g

e

ry

,

4

2

5

,

4

2

5

t

L

u

p

u

s

n

e

p

h

ri

t

i

s

(

L

N

)

,

6

2

5

–

6

2

6

L

u

t

e

a

l

p

h

a

s

e

s

u

p

p

o

rt

,

i

n

I

VF

,

9

6

5

L

V

(

s

e

e

L

e

ft

v

e

n

t

ri

c

u

l

a

r

(

L

V)

)

L

VE

D

P

(

s

e

e

L

e

ft

v

e

n

t

ri

c

u

l

a

r

e

n

d

-

d

i

a

s

t

o

l

i

c

p

r

e

s

s

u

r

e

(

L

VE

D

P

)

)

L

VE

D

V

(

s

e

e

L

e

ft

v

e

n

t

ri

c

u

l

a

r

e

n

d

-

d

i

a

s

t

o

l

i

c

v

o

l

u

m

e

(

L

VE

D

V)

)

L

VE

F

(

s

e

e

L

e

ft

v

e

n

t

ri

c

u

l

a

r

e

j

e

c

t

i

o

n

fr

a

c

t

i

o

n

(

L

VE

F

)

)

L

VH

(

s

e

e

L

e

ft

v

e

n

t

ri

c

u

l

a

r

h

yp

e

rt

r

o

p

h

y

(

L

VH

)

)

L

V

S

D

(

s

e

e

L

e

ft

v

e

n

t

ri

c

u

l

a

r

s

y

s

t

o

l

i

c

d

y

s

fu

n

c

t

i

o

n

(

L

V

S

D

)

)

L

y

m

e

d

i

s

e

a

s

e

,

1

7

2

9

L

y

m

p

h

o

c

yt

e

s

,

3

3

–

3

4

L

y

m

p

h

o

g

r

a

n

u

l

o

m

a

v

e

n

e

r

e

u

m

(

L

GV)

,

1

5

1

6

–

1

5

1

7

L

y

m

p

h

o

k

i

n

e

s

,

7

1

7

L

y

m

p

h

o

m

a

s

c

la

s

s

ific

a

t

io

n

o

f,

2

0

3

9

t

c

linic

a

l

p

r

e

s

e

nt

a

t

io

n

o

f,

2

0

3

9

dia

gn

o

s

is

o

f,

2

0

3