Figure 102-22. Video-assisted thoracoscopic treatment of complicated empyema in children. A: Chest radiograph of a 2-year-old
child presenting with pneumonia and pleural effusion. B: Computerized tomography demonstrates complicated pneumonia with
loculated empyema. C: Video endoscopic view of organized empyema debris. D: “Decortication” procedure includes removal of all
loculated, organized debris from the hemithorax. All surfaces of the visceral and parietal pleura are accessible using video
endoscopic techniques. E: Immediate postoperative chest x-ray shows the expected residual parenchymal lung disease. F: One
month later, the chest radiograph findings have resolved.
With a small amount of fluid, the empyema may resolve with antibiotics alone. When the collection
becomes larger, the treatment is drainage of the collection. Several trials have compared fibrinolytics to
video-assisted thoracoscopy (VATS). Both VATS and chest tube with fibrinolytics have been shown to be
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effective with a systematic review demonstrating no superiority of VATS.157 Other studies have
demonstrated improvement after VATS.158,159
Pneumothorax
Spontaneous pneumothorax is relatively uncommon. The etiology seems to be lung connective tissue
changes predisposing to leaks into the pleural space. This occurs in approximately 2.6 per 100,000
population of children requiring hospitalization in the United States in 2000. It has been suggested that
blebs are associated with the disease. The presentation is usually with chest pain and shortness of breath
but may also be associated with cough. The pain may be pleuritic in nature. Diagnosis is best confirmed
with chest radiograph.160 Chest CT has been utilized for identification of blebs but a negative
examination does not predict freedom from recurrence.161
Treatment of pneumothorax depends on the patient. Observation with or without high flow oxygen is
appropriate for the relatively asymptomatic patient. Chest tube placement is the next stage of
treatment. For recurrent pneumothoraces, intrapleural sclerosing agents such as talc can be used. VATS
with bleb resection and pleurodesis has also been described with good results.162
Chylothorax
Chylothorax which is the accumulation of chyle in the pleural space is a rare cause of effusion in
children but is the most common cause of effusion in the neonate.163 Chylothorax is associated with
pulmonary lymphangiomas and lymphangiectasia. Chylothorax may also be a manifestation of Down,
Turner, and Noonan syndromes. Chylothorax may occur due to trauma to the thoracic duct either
iatrogenic or noniatrogenic due to blunt trauma. Malignancy and granulomatous diseases may cause
obstruction of the thoracic duct leading to chylothorax.
The initial symptoms are related to accumulation of fluid in the pleural space with dyspnea, cough,
and chest discomfort. Pleuritic pain and fever are rare. Diagnosis is by chest radiograph combined with
findings on thoracentesis. The fluid is usually milky in appearance with triglycerides greater than 1.1
mmol/L, total cell count greater than 1,000 cells per microliter, and lymphocyte predominance greater
than 80%.164
Management consists of expansion of the lung with thoracentesis or tube thoracostomy. Minimization
of lymph flow is managed by either parenteral nutrition of diet manipulation using only dietary
medium-chain fatty acids. Long-term, this can lead to life-threatening immunologic problems. Surgical
management is then employed. Thoracic duct ligation can be performed either via thoracotomy or
thoracoscopic approach. This may require the administration of cream via a nasogastric tube in the
hours before surgery. If this fails, pleurectomy and pleurodesis or pleuroperitoneal shunting may be
employed.
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